4Filing Date: Oct 15, 2026

Regeneron (REGN) 4: MURPHY ANDREW J bought 17,000 shares at $381.92 on 2026-10-… (Oct 15, 2026)

Statement of Changes in Beneficial Ownership

View SEC Filing
ACC: 0001796226-26-000002
Total Value$19.40M
Trades31
Insiders1

Transaction Details

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-16
Price$757.68
Total Value$12.1K
Shares Owned After51.92K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-74
Price$760.65
Total Value$56.3K
Shares Owned After51.81K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 74 shares of Company stock on October 14, 2026 at prices ranging from $760.28 to $760.94. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-105
Price$768.33
Total Value$80.7K
Shares Owned After50.64K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 105 shares of Company stock on October 14, 2026 at prices ranging from $768.15 to $768.59. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-283
Price$771.56
Total Value$218.4K
Shares Owned After50.22K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 283 shares of Company stock on October 14, 2026 at prices ranging from $771.04 to $771.95. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-224
Price$773.40
Total Value$173.2K
Shares Owned After49.78K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 224 shares of Company stock on October 14, 2026 at prices ranging from $773.14 to $773.84. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-121
Price$774.48
Total Value$93.7K
Shares Owned After49.66K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 121 shares of Company stock on October 14, 2026 at prices ranging from $774.11 to $774.85. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-380
Price$779.59
Total Value$296.2K
Shares Owned After48.35K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 380 shares of Company stock on October 14, 2026 at prices ranging from $779.00 to $779.97. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-14
Price$759.96
Total Value$10.6K
Shares Owned After51.88K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 14 shares of Company stock on October 14, 2026 at prices ranging from $759.94 to $759.96. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-55
Price$762.57
Total Value$41.9K
Shares Owned After51.73K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-271
Price$765.39
Total Value$207.4K
Shares Owned After51.21K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 271 shares of Company stock on October 14, 2026 at prices ranging from $765.11 to $765.78. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-454
Price$778.64
Total Value$353.5K
Shares Owned After48.73K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 454 shares of Company stock on October 14, 2026 at prices ranging from $778.05 to $778.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-50
Price$781.47
Total Value$39.1K
Shares Owned After47.83K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 50 shares of Company stock on October 14, 2026 at prices ranging from $781.05 to $781.84. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-35
Price$755.91
Total Value$26.5K
Shares Owned After51.94K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-27
Price$761.36
Total Value$20.6K
Shares Owned After51.78K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 27 shares of Company stock on October 14, 2026 at prices ranging from $761.01 to $761.68. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-219
Price$764.40
Total Value$167.4K
Shares Owned After51.48K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 219 shares of Company stock on October 14, 2026 at prices ranging from $764.04 to $764.82. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-192
Price$767.39
Total Value$147.3K
Shares Owned After50.74K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 192 shares of Company stock on October 14, 2026 at prices ranging from $767.10 to $767.82. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-12
Price$770.20
Total Value$9.2K
Shares Owned After50.50K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-38
Price$777.76
Total Value$29.6K
Shares Owned After49.18K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 38 shares of Company stock on October 14, 2026 at prices ranging from $777.51 to $777.92. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-6
Price$753.76
Total Value$4.5K
Shares Owned After51.97K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-24
Price$758.16
Total Value$18.2K
Shares Owned After51.90K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-25
Price$763.76
Total Value$19.1K
Shares Owned After51.70K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 25 shares of Company stock on October 14, 2026 at prices ranging from $763.62 to $763.94. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-279
Price$766.47
Total Value$213.8K
Shares Owned After50.94K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 279 shares of Company stock on October 14, 2026 at prices ranging from $766.00 to $766.95. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-127
Price$769.30
Total Value$97.7K
Shares Owned After50.51K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 127 shares of Company stock on October 14, 2026 at prices ranging from $769.15 to $769.93. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-211
Price$772.56
Total Value$163.0K
Shares Owned After50.01K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 211 shares of Company stock on October 14, 2026 at prices ranging from $772.06 to $772.74. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-376
Price$775.46
Total Value$291.6K
Shares Owned After49.28K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 376 shares of Company stock on October 14, 2026 at prices ranging from $775.14 to $775.92. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-66
Price$776.31
Total Value$51.2K
Shares Owned After49.22K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 66 shares of Company stock on October 14, 2026 at prices ranging from $776.00 to $776.98. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Sell · Dispose
Common Stock
Shares-463
Price$780.63
Total Value$361.4K
Shares Owned After47.88K
Transaction DateOct 14, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | Represents volume-weighted average price of sales of 463 shares of Company stock on October 14, 2026 at prices ranging from $780.06 to $780.89. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Tax W/H · Dispose
Common Stock
Shares-12.85K
Price$754.58
Total Value$9.70M
Shares Owned After51.98K
Transaction DateOct 13, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Exercise · Acquire
Common Stock
Shares+17.00K
Price$381.92
Total Value$6.49M
Shares Owned After64.83K
Transaction DateOct 13, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026.

MURPHY ANDREW J
Co-Chief Scientific Officer·Direct
Exercise · Dispose
Non-Qualified Stock Option (right to buy)Derivative
Shares-17.00K
Price$0.00
Total Value$0
Shares Owned After17.00K
Transaction DateOct 13, 2026
Exercise Price$381.92
ExpiresDec 16, 2026
10b5-1
Footnotes ▸

Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. | The stock option award vested in four equal annual installments, commencing one year after the date of grant.

MURPHY ANDREW J
Co-Chief Scientific Officer·Indirect · By 401(k) Plan
Common Stock
Shares0
Price-
Total Value$0
Shares Owned After4.41K
10b5-1Holding Only

Post-Transaction Holdings

MURPHY ANDREW J · Co-Chief Scientific Officer
SecuritySharesChange
Common Stock56.34K-
Non-Qualified Stock Option (right to buy)17.00K-17.00K (-50.00%)
Original SEC Filing Textexpand_more
=== SEC Form 4 — Statement of Changes in Beneficial Ownership === Document Type: 4 Period of Report: 2026-10-13 10b5-1 Pre-arranged Plan: Yes --- Issuer --- Name: REGENERON PHARMACEUTICALS, INC. (REGN) CIK: 0000872589 --- Reporting Owner --- Name: MURPHY ANDREW J CIK: 0001796226 Role: Officer (Co-Chief Scientific Officer) --- Non-Derivative Transactions --- [Transaction #1] Security: Common Stock Date: 2026-10-13 | Code: M (Exercise of derivative) Shares: +17,000 | Price: $381.92 Total Value: $6,492,640.00 Shares Owned After: 64,833 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [Transaction #2] Security: Common Stock Date: 2026-10-13 | Code: F (Payment of exercise/tax) Shares: -12,853 | Price: $754.58 Total Value: $9,698,616.74 Shares Owned After: 51,980 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [Transaction #3] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -6 | Price: $753.76 Total Value: $4,522.56 Shares Owned After: 51,974 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [Transaction #4] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -35 | Price: $755.91 Total Value: $26,456.85 Shares Owned After: 51,939 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [Transaction #5] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -16 | Price: $757.68 Total Value: $12,122.88 Shares Owned After: 51,923 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [Transaction #6] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -24 | Price: $758.16 Total Value: $18,195.84 Shares Owned After: 51,899 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [Transaction #7] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -14 | Price: $759.96 Total Value: $10,639.44 Shares Owned After: 51,885 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F2] Represents volume-weighted average price of sales of 14 shares of Company stock on October 14, 2026 at prices ranging from $759.94 to $759.96. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #8] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -74 | Price: $760.65 Total Value: $56,288.10 Shares Owned After: 51,811 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F3] Represents volume-weighted average price of sales of 74 shares of Company stock on October 14, 2026 at prices ranging from $760.28 to $760.94. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #9] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -27 | Price: $761.36 Total Value: $20,556.72 Shares Owned After: 51,784 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F4] Represents volume-weighted average price of sales of 27 shares of Company stock on October 14, 2026 at prices ranging from $761.01 to $761.68. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #10] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -55 | Price: $762.57 Total Value: $41,941.35 Shares Owned After: 51,729 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [Transaction #11] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -25 | Price: $763.76 Total Value: $19,094.00 Shares Owned After: 51,704 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F5] Represents volume-weighted average price of sales of 25 shares of Company stock on October 14, 2026 at prices ranging from $763.62 to $763.94. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #12] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -219 | Price: $764.40 Total Value: $167,403.60 Shares Owned After: 51,485 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F6] Represents volume-weighted average price of sales of 219 shares of Company stock on October 14, 2026 at prices ranging from $764.04 to $764.82. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #13] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -271 | Price: $765.39 Total Value: $207,420.69 Shares Owned After: 51,214 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F7] Represents volume-weighted average price of sales of 271 shares of Company stock on October 14, 2026 at prices ranging from $765.11 to $765.78. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #14] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -279 | Price: $766.47 Total Value: $213,845.13 Shares Owned After: 50,935 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F8] Represents volume-weighted average price of sales of 279 shares of Company stock on October 14, 2026 at prices ranging from $766.00 to $766.95. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #15] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -192 | Price: $767.39 Total Value: $147,338.88 Shares Owned After: 50,743 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F9] Represents volume-weighted average price of sales of 192 shares of Company stock on October 14, 2026 at prices ranging from $767.10 to $767.82. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #16] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -105 | Price: $768.33 Total Value: $80,674.65 Shares Owned After: 50,638 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F10] Represents volume-weighted average price of sales of 105 shares of Company stock on October 14, 2026 at prices ranging from $768.15 to $768.59. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #17] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -127 | Price: $769.30 Total Value: $97,701.10 Shares Owned After: 50,511 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F11] Represents volume-weighted average price of sales of 127 shares of Company stock on October 14, 2026 at prices ranging from $769.15 to $769.93. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #18] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -12 | Price: $770.20 Total Value: $9,242.40 Shares Owned After: 50,499 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [Transaction #19] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -283 | Price: $771.56 Total Value: $218,351.48 Shares Owned After: 50,216 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F12] Represents volume-weighted average price of sales of 283 shares of Company stock on October 14, 2026 at prices ranging from $771.04 to $771.95. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #20] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -211 | Price: $772.56 Total Value: $163,010.16 Shares Owned After: 50,005 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F13] Represents volume-weighted average price of sales of 211 shares of Company stock on October 14, 2026 at prices ranging from $772.06 to $772.74. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #21] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -224 | Price: $773.40 Total Value: $173,241.60 Shares Owned After: 49,781 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F14] Represents volume-weighted average price of sales of 224 shares of Company stock on October 14, 2026 at prices ranging from $773.14 to $773.84. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #22] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -121 | Price: $774.48 Total Value: $93,712.08 Shares Owned After: 49,660 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F15] Represents volume-weighted average price of sales of 121 shares of Company stock on October 14, 2026 at prices ranging from $774.11 to $774.85. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #23] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -376 | Price: $775.46 Total Value: $291,572.96 Shares Owned After: 49,284 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F16] Represents volume-weighted average price of sales of 376 shares of Company stock on October 14, 2026 at prices ranging from $775.14 to $775.92. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #24] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -66 | Price: $776.31 Total Value: $51,236.46 Shares Owned After: 49,218 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F17] Represents volume-weighted average price of sales of 66 shares of Company stock on October 14, 2026 at prices ranging from $776.00 to $776.98. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #25] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -38 | Price: $777.76 Total Value: $29,554.88 Shares Owned After: 49,180 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F18] Represents volume-weighted average price of sales of 38 shares of Company stock on October 14, 2026 at prices ranging from $777.51 to $777.92. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #26] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -454 | Price: $778.64 Total Value: $353,502.56 Shares Owned After: 48,726 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F19] Represents volume-weighted average price of sales of 454 shares of Company stock on October 14, 2026 at prices ranging from $778.05 to $778.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #27] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -380 | Price: $779.59 Total Value: $296,244.20 Shares Owned After: 48,346 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F20] Represents volume-weighted average price of sales of 380 shares of Company stock on October 14, 2026 at prices ranging from $779.00 to $779.97. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #28] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -463 | Price: $780.63 Total Value: $361,431.69 Shares Owned After: 47,883 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F21] Represents volume-weighted average price of sales of 463 shares of Company stock on October 14, 2026 at prices ranging from $780.06 to $780.89. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. [Transaction #29] Security: Common Stock Date: 2026-10-14 | Code: S (Open market sale) Shares: -50 | Price: $781.47 Total Value: $39,073.50 Shares Owned After: 47,833 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F22] Represents volume-weighted average price of sales of 50 shares of Company stock on October 14, 2026 at prices ranging from $781.05 to $781.84. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. --- Derivative Transactions --- [Transaction #1] Security: Non-Qualified Stock Option (right to buy) Date: 2026-10-13 | Code: M (Exercise of derivative) Shares: -17,000 | Price: $0.00 Exercise Price: $381.92 Exercisable: N/A | Expires: 2026-12-16 Shares Owned After: 17,000 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. [F23] The stock option award vested in four equal annual installments, commencing one year after the date of grant. --- Holdings --- [Holding #1] Security: Common Stock Ownership: I (Indirect) --- Footnotes (Complete Index) --- F1: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on May 7, 2026. F10: Represents volume-weighted average price of sales of 105 shares of Company stock on October 14, 2026 at prices ranging from $768.15 to $768.59. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F11: Represents volume-weighted average price of sales of 127 shares of Company stock on October 14, 2026 at prices ranging from $769.15 to $769.93. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F12: Represents volume-weighted average price of sales of 283 shares of Company stock on October 14, 2026 at prices ranging from $771.04 to $771.95. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F13: Represents volume-weighted average price of sales of 211 shares of Company stock on October 14, 2026 at prices ranging from $772.06 to $772.74. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F14: Represents volume-weighted average price of sales of 224 shares of Company stock on October 14, 2026 at prices ranging from $773.14 to $773.84. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F15: Represents volume-weighted average price of sales of 121 shares of Company stock on October 14, 2026 at prices ranging from $774.11 to $774.85. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F16: Represents volume-weighted average price of sales of 376 shares of Company stock on October 14, 2026 at prices ranging from $775.14 to $775.92. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F17: Represents volume-weighted average price of sales of 66 shares of Company stock on October 14, 2026 at prices ranging from $776.00 to $776.98. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F18: Represents volume-weighted average price of sales of 38 shares of Company stock on October 14, 2026 at prices ranging from $777.51 to $777.92. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F19: Represents volume-weighted average price of sales of 454 shares of Company stock on October 14, 2026 at prices ranging from $778.05 to $778.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F2: Represents volume-weighted average price of sales of 14 shares of Company stock on October 14, 2026 at prices ranging from $759.94 to $759.96. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F20: Represents volume-weighted average price of sales of 380 shares of Company stock on October 14, 2026 at prices ranging from $779.00 to $779.97. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F21: Represents volume-weighted average price of sales of 463 shares of Company stock on October 14, 2026 at prices ranging from $780.06 to $780.89. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F22: Represents volume-weighted average price of sales of 50 shares of Company stock on October 14, 2026 at prices ranging from $781.05 to $781.84. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F23: The stock option award vested in four equal annual installments, commencing one year after the date of grant. F3: Represents volume-weighted average price of sales of 74 shares of Company stock on October 14, 2026 at prices ranging from $760.28 to $760.94. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F4: Represents volume-weighted average price of sales of 27 shares of Company stock on October 14, 2026 at prices ranging from $761.01 to $761.68. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F5: Represents volume-weighted average price of sales of 25 shares of Company stock on October 14, 2026 at prices ranging from $763.62 to $763.94. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F6: Represents volume-weighted average price of sales of 219 shares of Company stock on October 14, 2026 at prices ranging from $764.04 to $764.82. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F7: Represents volume-weighted average price of sales of 271 shares of Company stock on October 14, 2026 at prices ranging from $765.11 to $765.78. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F8: Represents volume-weighted average price of sales of 279 shares of Company stock on October 14, 2026 at prices ranging from $766.00 to $766.95. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. F9: Represents volume-weighted average price of sales of 192 shares of Company stock on October 14, 2026 at prices ranging from $767.10 to $767.82. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 14, 2026 at each separate price. --- Signature --- /s/ /s/ Andrew Murphy (2026-10-15)

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