Charles River (CRL)

=== SEC Form 4 — Statement of Changes in Beneficial Ownership === Document Type: 4 Period of Report: 2026-08-18 10b5-1 Pre-arranged Plan: No --- Issuer --- Name: CHARLES RIVER LABORATORIES INTERNATIONAL, INC. (CRL) CIK: 0001100682 --- Reporting Owner --- Name: Andrews Nancy C CIK: 0001804999 Role: Director --- Non-Derivative Transactions --- [Transaction #1] Security: Common Stock Date: 2026-08-18 | Code: M (Exercise of derivative) Shares: +573 | Price: $164.30 Total Value: $94,143.90 Shares Owned After: 2,011 | Ownership: D (Direct) [Transaction #2] Security: Common Stock Date: 2026-08-18 | Code: S (Open market sale) Shares: -573 | Price: $285.24 Total Value: $163,442.52 Shares Owned After: 1,438 | Ownership: D (Direct) --- Derivative Transactions --- [Transaction #1] Security: Stock Options (Right to Buy) Date: 2026-08-18 | Code: M (Exercise of derivative) Shares: -573 | Price: $0.00 Exercisable: N/A | Expires: 2027-03-02 Shares Owned After: 0 | Ownership: D (Direct) --- Holdings --- [Holding #1] Security: Common Stock Ownership: I (Indirect) --- Signature --- /s/ /s/ Nancy C. Andrews (2026-08-18)