Charles River (CRL)

=== SEC Form 4 — Statement of Changes in Beneficial Ownership === Document Type: 4 Period of Report: 2026-08-19 10b5-1 Pre-arranged Plan: Yes --- Issuer --- Name: CHARLES RIVER LABORATORIES INTERNATIONAL, INC. (CRL) CIK: 0001100682 --- Reporting Owner --- Name: Parisotto Shannon M CIK: 0001952784 Role: Officer (CEVP, Disc & Safety Assessment) --- Non-Derivative Transactions --- [Transaction #1] Security: Common Stock Date: 2026-08-19 | Code: M (Exercise of derivative) Shares: +2,039 | Price: $194.12 Total Value: $395,810.68 Shares Owned After: 6,846 | Ownership: D (Direct) [Transaction #2] Security: Common Stock Date: 2026-08-19 | Code: S (Open market sale) Shares: -2,039 | Price: $294.12 Total Value: $599,710.68 Shares Owned After: 4,807 | Ownership: D (Direct) Footnotes: [F1] This exercise and sale occurred pursuant to a Rule 10b5-1 Trading Plan that was initially adopted on March 4, 2026. --- Derivative Transactions --- [Transaction #1] Security: Stock Options (Right to Buy) Date: 2026-08-19 | Code: M (Exercise of derivative) Shares: -2,039 | Price: $0.00 Exercisable: N/A | Expires: 2033-05-26 Shares Owned After: 2,039 | Ownership: D (Direct) --- Holdings --- [Holding #1] Security: Common Stock Ownership: I (Indirect) [Holding #2] Security: Common Stock Ownership: I (Indirect) --- Footnotes (Complete Index) --- F1: This exercise and sale occurred pursuant to a Rule 10b5-1 Trading Plan that was initially adopted on March 4, 2026. --- Signature --- /s/ /s/ Shannon M. Parisotto (2026-08-19)