Bio-techne

=== SEC Form 4 — Statement of Changes in Beneficial Ownership === Document Type: 4 Period of Report: 2026-08-17 10b5-1 Pre-arranged Plan: No --- Issuer --- Name: BIO-TECHNE Corp (TECH) CIK: 0000842023 --- Reporting Owner --- Name: Hippel James CIK: 0001603594 Role: Officer (CFO) --- Derivative Transactions --- [Transaction #1] Security: Restricted Stock Units Date: 2026-08-17 | Code: A (Grant or award) Shares: +22,438 | Price: $0.00 Shares Owned After: 22,438 | Ownership: D (Direct) Footnotes: [F5] Each restricted stock unit represents a contingent right to receive one share of Bio-Techne Corporation common stock. [F11] 7,479 restricted stock units vest on each of 8/17/2027 and 8/17/2028, and 7,480 restricted stock units vest on 8/17/2029. [F11] 7,479 restricted stock units vest on each of 8/17/2027 and 8/17/2028, and 7,480 restricted stock units vest on 8/17/2029. [Transaction #2] Security: Restricted Stock Units Date: 2026-08-17 | Code: A (Grant or award) Shares: +36,459 | Price: $0.00 Shares Owned After: 36,459 | Ownership: D (Direct) Footnotes: [F5] Each restricted stock unit represents a contingent right to receive one share of Bio-Techne Corporation common stock. [F12] 36,459 restricted stock units vest on 8/17/2029. [F12] 36,459 restricted stock units vest on 8/17/2029. --- Holdings --- [Holding #1] Security: Common Stock Ownership: D (Direct) [Holding #2] Security: Stock Options (Right to Buy) Ownership: D (Direct) Footnotes: [F1] Fully exercisable. [Holding #3] Security: Stock Options (Right to Buy) Ownership: D (Direct) Footnotes: [F1] Fully exercisable. [Holding #4] Security: Stock Options (Right to Buy) Ownership: D (Direct) Footnotes: [F1] Fully exercisable. [Holding #5] Security: Stock Options (Right to Buy) Ownership: D (Direct) Footnotes: [F1] Fully exercisable. [Holding #6] Security: Stock Options (Right to Buy) Ownership: D (Direct) Footnotes: [F2] Options to purchase 11,481 shares vest on each of 8/15/2024, 8/15/2025 and 8/15/2027, and options to purchase 11,480 shares vest on 8/15/2026. [Holding #7] Security: Stock Options (Right to Buy) Ownership: D (Direct) Footnotes: [F3] Options to purchase 8,104 shares vest on each of 8/15/2025, 8/15/2026 and 8/15/2027, and options to purchase 8,105 shares vest on 8/15/2028. [Holding #8] Security: Stock Options (Right to Buy) Ownership: D (Direct) Footnotes: [F4] Options to purchase 12,544 shares vest on each of 8/15/2026, 8/15/2027 and 8/15/2028. [Holding #9] Security: Performance Restricted Stock Units Ownership: D (Direct) Footnotes: [F5] Each restricted stock unit represents a contingent right to receive one share of Bio-Techne Corporation common stock. [F6] Vests in full or in part on 8/15/2027 if certain performance goals are achieved (or such later date as performance is certified by the Administrator). [F6] Vests in full or in part on 8/15/2027 if certain performance goals are achieved (or such later date as performance is certified by the Administrator). [Holding #10] Security: Performance Restricted Stock Units Ownership: D (Direct) Footnotes: [F5] Each restricted stock unit represents a contingent right to receive one share of Bio-Techne Corporation common stock. [F7] Vests in full or in part on 8/15/2028 if certain performance goals are achieved (or such later date as performance is certified by the Administrator). [F7] Vests in full or in part on 8/15/2028 if certain performance goals are achieved (or such later date as performance is certified by the Administrator). [Holding #11] Security: Restricted Stock Units Ownership: D (Direct) Footnotes: [F5] Each restricted stock unit represents a contingent right to receive one share of Bio-Techne Corporation common stock. [F8] 4,011 restricted stock units vest on 8/15/2027. [F8] 4,011 restricted stock units vest on 8/15/2027. [Holding #12] Security: Restricted Stock Units Ownership: D (Direct) Footnotes: [F5] Each restricted stock unit represents a contingent right to receive one share of Bio-Techne Corporation common stock. [F9] 11,545 restricted stock units vest on 11/1/2026; and 11,544 restricted stock units vest on 11/1/2027. [F9] 11,545 restricted stock units vest on 11/1/2026; and 11,544 restricted stock units vest on 11/1/2027. [Holding #13] Security: Restricted Stock Units Ownership: D (Direct) Footnotes: [F5] Each restricted stock unit represents a contingent right to receive one share of Bio-Techne Corporation common stock. [F10] 4,903 restricted stock units vest on 8/15/2027, and 4,904 restricted stock units vest on 8/15/2028. [F10] 4,903 restricted stock units vest on 8/15/2027, and 4,904 restricted stock units vest on 8/15/2028. --- Footnotes (Complete Index) --- F1: Fully exercisable. F10: 4,903 restricted stock units vest on 8/15/2027, and 4,904 restricted stock units vest on 8/15/2028. F11: 7,479 restricted stock units vest on each of 8/17/2027 and 8/17/2028, and 7,480 restricted stock units vest on 8/17/2029. F12: 36,459 restricted stock units vest on 8/17/2029. F2: Options to purchase 11,481 shares vest on each of 8/15/2024, 8/15/2025 and 8/15/2027, and options to purchase 11,480 shares vest on 8/15/2026. F3: Options to purchase 8,104 shares vest on each of 8/15/2025, 8/15/2026 and 8/15/2027, and options to purchase 8,105 shares vest on 8/15/2028. F4: Options to purchase 12,544 shares vest on each of 8/15/2026, 8/15/2027 and 8/15/2028. F5: Each restricted stock unit represents a contingent right to receive one share of Bio-Techne Corporation common stock. F6: Vests in full or in part on 8/15/2027 if certain performance goals are achieved (or such later date as performance is certified by the Administrator). F7: Vests in full or in part on 8/15/2028 if certain performance goals are achieved (or such later date as performance is certified by the Administrator). F8: 4,011 restricted stock units vest on 8/15/2027. F9: 11,545 restricted stock units vest on 11/1/2026; and 11,544 restricted stock units vest on 11/1/2027. --- Signature --- /s/ /s/ Andrew Nick as Attorney-in-Fact for James Hippel pursuant to Power of Attorney previously filed (2026-08-19)