Guardant Health (GH)

=== SEC Form 4 — Statement of Changes in Beneficial Ownership === Document Type: 4 Period of Report: 2026-08-10 10b5-1 Pre-arranged Plan: No --- Issuer --- Name: Guardant Health, Inc. (GH) CIK: 0001576280 --- Reporting Owner --- Name: Talasaz AmirAli CIK: 0001753159 Role: Director, Officer (Co-Chief Executive Officer) --- Non-Derivative Transactions --- [Transaction #1] Security: Common Stock Date: 2026-08-10 | Code: G (Gift) Shares: -75,000 | Price: $0.00 Shares Owned After: 1,824,351 | Ownership: I (Indirect) | Nature: Shares held by Talasaz and Eskandari 2017 Family Trust Footnotes: [F1] Reflects changes in form of ownership from Talasaz and Eskandari 2017 Family Trust due to the gift of shares to The Talasaz Family Foundation. [Transaction #2] Security: Common Stock Date: 2026-08-10 | Code: G (Gift) Shares: +75,000 | Price: $0.00 Shares Owned After: 75,000 | Ownership: I (Indirect) | Nature: Shares held by the Talasaz Family Foundation Footnotes: [F1] Reflects changes in form of ownership from Talasaz and Eskandari 2017 Family Trust due to the gift of shares to The Talasaz Family Foundation. --- Footnotes (Complete Index) --- F1: Reflects changes in form of ownership from Talasaz and Eskandari 2017 Family Trust due to the gift of shares to The Talasaz Family Foundation. --- Signature --- /s/ /s/ John G. Saia, as attorney-in-fact for AmirAli Talasaz (2026-08-12)