Tempus AI

=== SEC Form 4 — Statement of Changes in Beneficial Ownership === Document Type: 4 Period of Report: 2026-08-07 10b5-1 Pre-arranged Plan: Yes --- Issuer --- Name: Tempus AI, Inc. (TEM) CIK: 0001717115 --- Reporting Owner --- Name: Fukushima Ryan CIK: 0002024250 Role: Officer (CEO, Data) --- Non-Derivative Transactions --- [Transaction #1] Security: Class A Common Stock Date: 2026-08-07 | Code: S (Open market sale) Shares: -20,000 | Price: $50.04 Total Value: $1,000,800.00 Shares Owned After: 123,945 | Ownership: I (Indirect) | Nature: By Spouse Footnotes: [F1] This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person's spouse on March 12, 2026. [F2] The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.00 to $50.15 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. --- Holdings --- [Holding #1] Security: Class A Common Stock Ownership: D (Direct) --- Footnotes (Complete Index) --- F1: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person's spouse on March 12, 2026. F2: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.00 to $50.15 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. --- Signature --- /s/ /s/ Andrew Polovin, Attorney-in-Fact (2026-08-11)