Charles River (CRL)

=== SEC Form 4 — Statement of Changes in Beneficial Ownership === Document Type: 4 Period of Report: 2026-08-06 10b5-1 Pre-arranged Plan: No --- Issuer --- Name: CHARLES RIVER LABORATORIES INTERNATIONAL, INC. (CRL) CIK: 0001100682 --- Reporting Owner --- Name: Creamer Victoria L CIK: 0001632780 Role: Officer (EVP & Chief People Officer) --- Non-Derivative Transactions --- [Transaction #1] Security: Common Stock Date: 2026-08-06 | Code: M (Exercise of derivative) Shares: +4,179 | Price: $179.66 Total Value: $750,799.14 Shares Owned After: 34,230 | Ownership: D (Direct) [Transaction #2] Security: Common Stock Date: 2026-08-06 | Code: S (Open market sale) Shares: -4,179 | Price: $259.16 Total Value: $1,083,029.64 Shares Owned After: 30,051 | Ownership: D (Direct) --- Derivative Transactions --- [Transaction #1] Security: Stock Options (Right to Buy) Date: 2026-08-06 | Code: M (Exercise of derivative) Shares: -4,179 | Price: $0.00 Exercisable: N/A | Expires: 2030-05-29 Shares Owned After: 0 | Ownership: D (Direct) --- Signature --- /s/ /s/ Victoria L. Creamer (2026-08-10)