AMGEN INC (AMGN) · Insider Trading (Form 4) SEC Filing

=== SEC Form 4 — Statement of Changes in Beneficial Ownership === Document Type: 4 Period of Report: 2026-08-06 10b5-1 Pre-arranged Plan: No --- Issuer --- Name: AMGEN INC (AMGN) CIK: 0000318154 --- Reporting Owner --- Name: Grygiel Nancy A. CIK: 0001816414 Role: Officer (SVP & CCO) --- Non-Derivative Transactions --- [Transaction #1] Security: Common Stock Date: 2026-08-06 | Code: M (Exercise of derivative) Shares: +1,970 | Price: $177.46 Total Value: $349,596.20 Shares Owned After: 9,310 | Ownership: D (Direct) [Transaction #2] Security: Common Stock Date: 2026-08-06 | Code: S (Open market sale) Shares: -1,970 | Price: $402.16 Total Value: $792,255.40 Shares Owned After: 7,340 | Ownership: D (Direct) Footnotes: [F1] Includes shares sold to cover the option exercise price and required withholding taxes in connection with the exercise of expiring options. [Transaction #3] Security: Common Stock Date: 2026-08-06 | Code: M (Exercise of derivative) Shares: +1,000 | Price: $177.31 Total Value: $177,310.00 Shares Owned After: 8,340 | Ownership: D (Direct) [Transaction #4] Security: Common Stock Date: 2026-08-06 | Code: S (Open market sale) Shares: -1,000 | Price: $402.16 Total Value: $402,160.10 Shares Owned After: 7,340 | Ownership: D (Direct) Footnotes: [F1] Includes shares sold to cover the option exercise price and required withholding taxes in connection with the exercise of expiring options. [F2] These shares include 68 Dividend Equivalents (DEs) granted pursuant to the Amgen Inc. Second Amended and Restated 2009 Equity Incentive Plan and subject to a qualifying dividend reinvestment plan. DEs are credited to the reporting person's unvested Restricted Stock Units and are paid out in shares of the Company's common stock on a one-to-one basis according to the vesting schedule, along with a cash payment for any remaining fractional share amount. --- Derivative Transactions --- [Transaction #1] Security: Nqso (Right to Buy) Date: 2026-08-06 | Code: M (Exercise of derivative) Shares: -1,970 | Price: $0.00 Exercisable: N/A | Expires: 2028-04-27 Shares Owned After: 0 | Ownership: D (Direct) [Transaction #2] Security: Nqso (Right to Buy) Date: 2026-08-06 | Code: M (Exercise of derivative) Shares: -1,000 | Price: $0.00 Exercisable: N/A | Expires: 2029-05-03 Shares Owned After: 2,948 | Ownership: D (Direct) --- Holdings --- [Holding #1] Security: Common Stock Ownership: I (Indirect) Footnotes: [F3] These shares are acquired under the Company's 401(k) Plan and represent interests in the Company's stock fund as of this filing. --- Footnotes (Complete Index) --- F1: Includes shares sold to cover the option exercise price and required withholding taxes in connection with the exercise of expiring options. F2: These shares include 68 Dividend Equivalents (DEs) granted pursuant to the Amgen Inc. Second Amended and Restated 2009 Equity Incentive Plan and subject to a qualifying dividend reinvestment plan. DEs are credited to the reporting person's unvested Restricted Stock Units and are paid out in shares of the Company's common stock on a one-to-one basis according to the vesting schedule, along with a cash payment for any remaining fractional share amount. F3: These shares are acquired under the Company's 401(k) Plan and represent interests in the Company's stock fund as of this filing. --- Signature --- /s/ /s/ Nancy A. Grygiel (2026-08-06)