Guardant Health, Inc. (GH) · Insider Trading (Form 4) SEC Filing

=== SEC Form 4 — Statement of Changes in Beneficial Ownership === Document Type: 4 Period of Report: 2026-08-04 10b5-1 Pre-arranged Plan: No --- Issuer --- Name: Guardant Health, Inc. (GH) CIK: 0001576280 --- Reporting Owner --- Name: CLARK IAN T CIK: 0001336504 Role: Director --- Non-Derivative Transactions --- [Transaction #1] Security: Common Stock Date: 2026-08-04 | Code: M (Exercise of derivative) Shares: +2,255 | Price: $91.11 Total Value: $205,453.05 Shares Owned After: 10,322 | Ownership: I (Indirect) | Nature: By The Thornton-Clark Family Trust, J Thornton-Clark & I Clark TTE Account [Transaction #2] Security: Common Stock Date: 2026-08-04 | Code: M (Exercise of derivative) Shares: +6,833 | Price: $50.57 Total Value: $345,544.81 Shares Owned After: 17,155 | Ownership: I (Indirect) | Nature: By The Thornton-Clark Family Trust, J Thornton-Clark & I Clark TTE Account [Transaction #3] Security: Common Stock Date: 2026-08-04 | Code: S (Open market sale) Shares: -9,088 | Price: $158.98 Total Value: $1,444,824.78 Shares Owned After: 8,067 | Ownership: I (Indirect) | Nature: By The Thornton-Clark Family Trust, J Thornton-Clark & I Clark TTE Account Footnotes: [F1] Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $158.510 to $159.435. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range. [Transaction #4] Security: Common Stock Date: 2026-08-04 | Code: S (Open market sale) Shares: -5,092 | Price: $158.80 Total Value: $808,625.89 Shares Owned After: 2,975 | Ownership: I (Indirect) | Nature: By The Thornton-Clark Family Trust, J Thornton-Clark & I Clark TTE Account Footnotes: [F2] Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $158.51 to $159.14. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range. --- Derivative Transactions --- [Transaction #1] Security: Stock Option (Right to Buy) Date: 2026-08-04 | Code: M (Exercise of derivative) Shares: -2,255 | Price: $0.00 Exercisable: N/A | Expires: 2029-06-18 Shares Owned After: 0 | Ownership: D (Direct) Footnotes: [F3] The stock option vested in full on June 12, 2020. [Transaction #2] Security: Stock Option (Right to Buy) Date: 2026-08-04 | Code: M (Exercise of derivative) Shares: -6,833 | Price: $0.00 Exercisable: N/A | Expires: 2035-06-18 Shares Owned After: 0 | Ownership: D (Direct) Footnotes: [F4] The stock option vested in full on June 17, 2026. --- Footnotes (Complete Index) --- F1: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $158.510 to $159.435. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range. F2: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $158.51 to $159.14. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range. F3: The stock option vested in full on June 12, 2020. F4: The stock option vested in full on June 17, 2026. --- Signature --- /s/ /s/ John G. Saia, as attorney-in-fact for Ian T. Clark (2026-08-05)