INCYTE CORP (INCY) · Insider Trading (Form 4) SEC Filing

=== SEC Form 4 — Statement of Changes in Beneficial Ownership === Document Type: 4 Period of Report: 2026-07-16 10b5-1 Pre-arranged Plan: No --- Issuer --- Name: INCYTE CORP (INCY) CIK: 0000879169 --- Reporting Owner --- Name: Mayes Patrick A CIK: 0002079962 Role: Officer (EVP & Chief Scientific Officer) --- Non-Derivative Transactions --- [Transaction #1] Security: Common Stock Date: 2026-07-16 | Code: A (Grant or award) Shares: +5,916 | Price: $0.00 Shares Owned After: 63,628 | Ownership: D (Direct) Footnotes: [F1] Represents award of restricted stock units ("RSUs") that will vest 25% annually over four years. The RSUs may be settled only for shares of common stock on a one-for-one basis. [F2] Including the July 16, 2026 grant, this includes an aggregate of 74,327 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested. --- Derivative Transactions --- [Transaction #1] Security: Performance Shares Date: 2026-07-16 | Code: A (Grant or award) Shares: +14,790 | Price: $0.00 Exercisable: N/A | Expires: 2029-07-16 Shares Owned After: 14,790 | Ownership: D (Direct) Footnotes: [F3] Each performance share represents the right to receive up to 200% of one share of common stock. Such shares may be earned based upon the issuer's relative total shareholder return ("TSR") over a three-year performance period beginning on January 1, 2026 as compared to the TSR of companies in a fixed peer group, as set forth in the Performance Share Award Agreement. The earned shares will vest on the third anniversary of the grant date subject to the Reporting Person's continued service with the issuer. [F3] Each performance share represents the right to receive up to 200% of one share of common stock. Such shares may be earned based upon the issuer's relative total shareholder return ("TSR") over a three-year performance period beginning on January 1, 2026 as compared to the TSR of companies in a fixed peer group, as set forth in the Performance Share Award Agreement. The earned shares will vest on the third anniversary of the grant date subject to the Reporting Person's continued service with the issuer. [Transaction #2] Security: Employee Stock Option (right to buy) Date: 2026-07-16 | Code: A (Grant or award) Shares: +25,538 | Price: $0.00 Exercisable: N/A | Expires: 2036-07-15 Shares Owned After: 25,538 | Ownership: D (Direct) Footnotes: [F4] The July 16, 2026 options become exercisable in 37 installments, with the first 25% vesting after one year and the remainder vesting monthly over three years. Remarks: --- Footnotes (Complete Index) --- F1: Represents award of restricted stock units ("RSUs") that will vest 25% annually over four years. The RSUs may be settled only for shares of common stock on a one-for-one basis. F2: Including the July 16, 2026 grant, this includes an aggregate of 74,327 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested. F3: Each performance share represents the right to receive up to 200% of one share of common stock. Such shares may be earned based upon the issuer's relative total shareholder return ("TSR") over a three-year performance period beginning on January 1, 2026 as compared to the TSR of companies in a fixed peer group, as set forth in the Performance Share Award Agreement. The earned shares will vest on the third anniversary of the grant date subject to the Reporting Person's continued service with the issuer. F4: The July 16, 2026 options become exercisable in 37 installments, with the first 25% vesting after one year and the remainder vesting monthly over three years. Remarks: --- Signature --- /s/ /s/ Elizabeth Feeney, Attorney-In-Fact (2026-07-20)