INCYTE CORP (INCY) · Insider Trading (Form 4) SEC Filing

=== SEC Form 4 — Statement of Changes in Beneficial Ownership === Document Type: 4 Period of Report: 2026-07-14 10b5-1 Pre-arranged Plan: No --- Issuer --- Name: INCYTE CORP (INCY) CIK: 0000879169 --- Reporting Owner --- Name: Mayes Patrick A CIK: 0002079962 Role: Officer (EVP & Chief Scientific Officer) --- Non-Derivative Transactions --- [Transaction #1] Security: Common Stock Date: 2026-07-14 | Code: F (Payment of exercise/tax) Shares: -437 | Price: $114.88 Total Value: $50,202.56 Shares Owned After: 59,224 | Ownership: D (Direct) Footnotes: [F1] Represents shares withheld automatically by the Issuer to satisfy tax withholding obligations due at settlement of restricted stock units previously reported in Table I as common stock. [Transaction #2] Security: Common Stock Date: 2026-07-15 | Code: F (Payment of exercise/tax) Shares: -1,512 | Price: $115.09 Total Value: $174,016.08 Shares Owned After: 57,712 | Ownership: D (Direct) Footnotes: [F1] Represents shares withheld automatically by the Issuer to satisfy tax withholding obligations due at settlement of restricted stock units previously reported in Table I as common stock. [F2] Includes an aggregate of 53,621 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested. --- Footnotes (Complete Index) --- F1: Represents shares withheld automatically by the Issuer to satisfy tax withholding obligations due at settlement of restricted stock units previously reported in Table I as common stock. F2: Includes an aggregate of 53,621 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested. --- Signature --- /s/ /s/ Elizabeth Feeney, Attorney-In-Fact (2026-07-16)