Guardant Health (GH)

=== SEC Form 4 — Statement of Changes in Beneficial Ownership === Document Type: 4 Period of Report: 2025-12-31 10b5-1 Pre-arranged Plan: No --- Issuer --- Name: Guardant Health, Inc. (GH) CIK: 0001576280 --- Reporting Owner --- Name: Krognes Steve E. CIK: 0001666236 Role: Director --- Non-Derivative Transactions --- [Transaction #1] Security: Common Stock Date: 2025-12-31 | Code: M (Exercise of derivative) Shares: +154 | Price: $0.00 Shares Owned After: 18,745 | Ownership: D (Direct) --- Derivative Transactions --- [Transaction #1] Security: Restricted Stock Units Date: 2025-12-31 | Code: M (Exercise of derivative) Shares: -154 | Price: $0.00 Shares Owned After: 926 | Ownership: D (Direct) Footnotes: [F1] This represents a restricted stock unit award granted on August 9, 2022 that vested 25% of the shares subject to such award on June 30, 2023. The remaining 75% of the shares subject to such award vests in substantially equal installments on each monthly anniversary of June 30, 2023, during the three-year period thereafter. [F2] Not applicable for Restricted Stock Units. --- Footnotes (Complete Index) --- F1: This represents a restricted stock unit award granted on August 9, 2022 that vested 25% of the shares subject to such award on June 30, 2023. The remaining 75% of the shares subject to such award vests in substantially equal installments on each monthly anniversary of June 30, 2023, during the three-year period thereafter. F2: Not applicable for Restricted Stock Units. --- Signature --- /s/ /s/ John Saia, as attorney-in-fact for Steve Krognes (2026-01-02)