Guardant Health (GH) 4: Monroe Terilyn J. bought 17,379 shares of Common Stock at $… (Jan 16, 2026)

=== SEC Form 4 — Statement of Changes in Beneficial Ownership === Document Type: 4 Period of Report: 2026-01-15 10b5-1 Pre-arranged Plan: No --- Issuer --- Name: Guardant Health, Inc. (GH) CIK: 0001576280 --- Reporting Owner --- Name: Monroe Terilyn J. CIK: 0001652956 Role: Officer (Chief People Officer) --- Non-Derivative Transactions --- [Transaction #1] Security: Common Stock Date: 2026-01-15 | Code: M (Exercise of derivative) Shares: +17,379 | Price: $0.00 Shares Owned After: 38,369 | Ownership: D (Direct) [Transaction #2] Security: Common Stock Date: 2026-01-15 | Code: F (Payment of exercise/tax) Shares: -8,808 | Price: $111.98 Total Value: $986,319.84 Shares Owned After: 29,561 | Ownership: D (Direct) Footnotes: [F1] These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability. --- Derivative Transactions --- [Transaction #1] Security: Restricted Stock Units Date: 2026-01-15 | Code: M (Exercise of derivative) Shares: -17,379 | Price: $0.00 Shares Owned After: 17,379 | Ownership: D (Direct) Footnotes: [F2] This represents a restricted stock unit award granted on February 26, 2024 that vests over a three-year period. 33% of the shares subject to such award vested on the one-year anniversary of January 15, 2024 and the remaining 67% of the shares vest annually over the remaining two-year period, thereafter. [F3] Not applicable for Restricted Stock Units. --- Footnotes (Complete Index) --- F1: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability. F2: This represents a restricted stock unit award granted on February 26, 2024 that vests over a three-year period. 33% of the shares subject to such award vested on the one-year anniversary of January 15, 2024 and the remaining 67% of the shares vest annually over the remaining two-year period, thereafter. F3: Not applicable for Restricted Stock Units. --- Signature --- /s/ /s/ John G. Saia, as attorney-in-fact for Tarilyn J. Monroe (2026-01-16)