REGENERON PHARMACEUTICALS, INC. (REGN) · Insider Trading (Form 4) SEC Filing

=== SEC Form 4 — Statement of Changes in Beneficial Ownership === Document Type: 4 Period of Report: 2026-03-02 10b5-1 Pre-arranged Plan: Yes --- Issuer --- Name: REGENERON PHARMACEUTICALS, INC. (REGN) CIK: 0000872589 --- Reporting Owner --- Name: RYAN ARTHUR F CIK: 0001187443 Role: Director --- Non-Derivative Transactions --- [Transaction #1] Security: Common Stock Date: 2026-03-02 | Code: S (Open market sale) Shares: -7 | Price: $777.46 Total Value: $5,442.22 Shares Owned After: 17,796 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on October 31, 2025. [F2] Represents volume-weighted average price of sales of 7 shares of Company stock on March 2, 2026 at prices ranging from $777.08 to $777.91. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. [Transaction #2] Security: Common Stock Date: 2026-03-02 | Code: S (Open market sale) Shares: -2 | Price: $778.30 Total Value: $1,556.60 Shares Owned After: 17,794 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on October 31, 2025. [F3] Represents volume-weighted average price of sales of 2 shares of Company stock on March 2, 2026 at prices ranging from $778.27 to $778.33. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. [Transaction #3] Security: Common Stock Date: 2026-03-02 | Code: S (Open market sale) Shares: -5 | Price: $779.69 Total Value: $3,898.45 Shares Owned After: 17,789 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on October 31, 2025. [F4] Represents volume-weighted average price of sales of 5 shares of Company stock on March 2, 2026 at prices ranging from $779.36 to $779.95. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. [Transaction #4] Security: Common Stock Date: 2026-03-02 | Code: S (Open market sale) Shares: -3 | Price: $780.69 Total Value: $2,342.07 Shares Owned After: 17,786 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on October 31, 2025. [F5] Represents volume-weighted average price of sales of 3 shares of Company stock on March 2, 2026 at prices ranging from $780.13 to $780.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. [Transaction #5] Security: Common Stock Date: 2026-03-02 | Code: S (Open market sale) Shares: -2 | Price: $781.21 Total Value: $1,562.42 Shares Owned After: 17,784 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on October 31, 2025. [F6] Represents volume-weighted average price of sales of 2 shares of Company stock on March 2, 2026 at prices ranging from $781.00 to $781.42. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. [Transaction #6] Security: Common Stock Date: 2026-03-02 | Code: S (Open market sale) Shares: -2 | Price: $782.62 Total Value: $1,565.24 Shares Owned After: 17,782 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on October 31, 2025. [F7] Represents volume-weighted average price of sales of 2 shares of Company stock on March 2, 2026 at prices ranging from $782.25 to $782.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. [Transaction #7] Security: Common Stock Date: 2026-03-02 | Code: S (Open market sale) Shares: -10 | Price: $783.62 Total Value: $7,836.20 Shares Owned After: 17,772 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on October 31, 2025. [F8] Represents volume-weighted average price of sales of 10 shares of Company stock on March 2, 2026 at prices ranging from $783.25 to $783.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. [Transaction #8] Security: Common Stock Date: 2026-03-02 | Code: S (Open market sale) Shares: -9 | Price: $784.48 Total Value: $7,060.32 Shares Owned After: 17,763 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on October 31, 2025. [F9] Represents volume-weighted average price of sales of 9 shares of Company stock on March 2, 2026 at prices ranging from $784.02 to $784.95. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. [Transaction #9] Security: Common Stock Date: 2026-03-02 | Code: S (Open market sale) Shares: -11 | Price: $785.48 Total Value: $8,640.28 Shares Owned After: 17,752 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on October 31, 2025. [F10] Represents volume-weighted average price of sales of 11 shares of Company stock on March 2, 2026 at prices ranging from $785.02 to $785.97. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. [Transaction #10] Security: Common Stock Date: 2026-03-02 | Code: S (Open market sale) Shares: -7 | Price: $786.61 Total Value: $5,506.27 Shares Owned After: 17,745 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on October 31, 2025. [F11] Represents volume-weighted average price of sales of 7 shares of Company stock on March 2, 2026 at prices ranging from $786.12 to $786.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. [Transaction #11] Security: Common Stock Date: 2026-03-02 | Code: S (Open market sale) Shares: -2 | Price: $787.34 Total Value: $1,574.68 Shares Owned After: 17,743 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on October 31, 2025. [F12] Represents volume-weighted average price of sales of 2 shares of Company stock on March 2, 2026 at prices ranging from $787.02 to $787.66. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. [Transaction #12] Security: Common Stock Date: 2026-03-02 | Code: S (Open market sale) Shares: -20 | Price: $788.96 Total Value: $15,779.20 Shares Owned After: 17,723 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on October 31, 2025. [Transaction #13] Security: Common Stock Date: 2026-03-02 | Code: S (Open market sale) Shares: -20 | Price: $789.28 Total Value: $15,785.60 Shares Owned After: 17,703 | Ownership: D (Direct) Footnotes: [F1] Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on October 31, 2025. [F13] Represents volume-weighted average price of sales of 20 shares of Company stock on March 2, 2026 at prices ranging from $789.27 to $789.37. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. --- Footnotes (Complete Index) --- F1: Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c) adopted on October 31, 2025. F10: Represents volume-weighted average price of sales of 11 shares of Company stock on March 2, 2026 at prices ranging from $785.02 to $785.97. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. F11: Represents volume-weighted average price of sales of 7 shares of Company stock on March 2, 2026 at prices ranging from $786.12 to $786.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. F12: Represents volume-weighted average price of sales of 2 shares of Company stock on March 2, 2026 at prices ranging from $787.02 to $787.66. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. F13: Represents volume-weighted average price of sales of 20 shares of Company stock on March 2, 2026 at prices ranging from $789.27 to $789.37. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. F2: Represents volume-weighted average price of sales of 7 shares of Company stock on March 2, 2026 at prices ranging from $777.08 to $777.91. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. F3: Represents volume-weighted average price of sales of 2 shares of Company stock on March 2, 2026 at prices ranging from $778.27 to $778.33. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. F4: Represents volume-weighted average price of sales of 5 shares of Company stock on March 2, 2026 at prices ranging from $779.36 to $779.95. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. F5: Represents volume-weighted average price of sales of 3 shares of Company stock on March 2, 2026 at prices ranging from $780.13 to $780.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. F6: Represents volume-weighted average price of sales of 2 shares of Company stock on March 2, 2026 at prices ranging from $781.00 to $781.42. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. F7: Represents volume-weighted average price of sales of 2 shares of Company stock on March 2, 2026 at prices ranging from $782.25 to $782.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. F8: Represents volume-weighted average price of sales of 10 shares of Company stock on March 2, 2026 at prices ranging from $783.25 to $783.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. F9: Represents volume-weighted average price of sales of 9 shares of Company stock on March 2, 2026 at prices ranging from $784.02 to $784.95. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on March 2, 2026 at each separate price. --- Signature --- /s/ /s/ Arthur F. Ryan (2026-03-03)