BIO-TECHNE Corp (TECH) · Insider Trading (Form 4) SEC Filing

=== SEC Form 4 — Statement of Changes in Beneficial Ownership === Document Type: 4 Period of Report: 2026-05-01 10b5-1 Pre-arranged Plan: No --- Issuer --- Name: BIO-TECHNE Corp (TECH) CIK: 0000842023 --- Reporting Owner --- Name: Crouse Steven C. CIK: 0002065241 Role: Officer (President - Diag & Spatial Bi) --- Non-Derivative Transactions --- [Transaction #1] Security: Common Stock Date: 2026-05-01 | Code: M (Exercise of derivative) Shares: +794 Shares Owned After: 6,688 | Ownership: D (Direct) Footnotes: [F1] Each restricted stock unit represents a contingent right to receive one share of Bio-Techne common stock. [Transaction #2] Security: Common Stock Date: 2026-05-01 | Code: F (Payment of exercise/tax) Shares: -311 | Price: $55.02 Total Value: $17,111.22 Shares Owned After: 6,337 | Ownership: D (Direct) --- Derivative Transactions --- [Transaction #1] Security: Restricted Stock Units Date: 2026-05-01 | Code: M (Exercise of derivative) Shares: -794 | Price: $0.00 Shares Owned After: 794 | Ownership: D (Direct) Footnotes: [F1] Each restricted stock unit represents a contingent right to receive one share of Bio-Techne common stock. [F2] 794 restricted stock units vest on 5/1/2026 and 5/1/2027. [F2] 794 restricted stock units vest on 5/1/2026 and 5/1/2027. --- Holdings --- [Holding #1] Security: Restricted Stock Units Ownership: D (Direct) Footnotes: [F1] Each restricted stock unit represents a contingent right to receive one share of Bio-Techne common stock. [F3] 600 restricted stock units vest on each of 6/2/2026, 6/2/2027 and 6/2/2028. [F3] 600 restricted stock units vest on each of 6/2/2026, 6/2/2027 and 6/2/2028. [Holding #2] Security: Restricted Stock Units Ownership: D (Direct) Footnotes: [F1] Each restricted stock unit represents a contingent right to receive one share of Bio-Techne common stock. [F4] 1,379 restricted stock units vest on 8/15/2026. [F4] 1,379 restricted stock units vest on 8/15/2026. [Holding #3] Security: Restricted Stock Units Ownership: D (Direct) Footnotes: [F1] Each restricted stock unit represents a contingent right to receive one share of Bio-Techne common stock. [F5] 1,868 restricted stock units vest on 8/15/2026 and 1,869 restricted stock units vest on 8/15/2027. [F5] 1,868 restricted stock units vest on 8/15/2026 and 1,869 restricted stock units vest on 8/15/2027. [Holding #4] Security: Restricted Stock Units Ownership: D (Direct) Footnotes: [F1] Each restricted stock unit represents a contingent right to receive one share of Bio-Techne common stock. [F6] 2,176 restricted stock units vest on each of 8/15/2026 and 8/15/2028; and 2,177 restricted stock units vest on 8/15/2027. [F6] 2,176 restricted stock units vest on each of 8/15/2026 and 8/15/2028; and 2,177 restricted stock units vest on 8/15/2027. [Holding #5] Security: Stock Option (right to buy) Ownership: D (Direct) Footnotes: [F7] 100% vested. [Holding #6] Security: Stock Option (right to buy) Ownership: D (Direct) Footnotes: [F7] 100% vested. [Holding #7] Security: Stock Option (right to buy) Ownership: D (Direct) Footnotes: [F8] Options to purchase 6,140 shares vest on each of 8/15/2023, 8/15/2024, 8/15/2025 and 8/15/2026. [Holding #8] Security: Stock Option (right to buy) Ownership: D (Direct) Footnotes: [F9] Options to purchase 3,162 shares vest on each of 8/15/2024, 8/15/2026 and 8/15/2027; and options to purchase 3,163 shares vest on 8/15/2025. [Holding #9] Security: Stock Option (right to buy) Ownership: D (Direct) Footnotes: [F10] Options to purchase 1,832 shares vest on each of 5/1/2025, 5/1/2026 and 5/1/2028; and options to purchase 1,831 shares vest on 5/1/2027. [Holding #10] Security: Stock Option (right to buy) Ownership: D (Direct) Footnotes: [F11] Options to purchase 4,283 shares vest on each of 8/15/2025, 8/15/2027 and 8/15/2028; and options to purchase 4,284 shares vest on 8/15/2026. [Holding #11] Security: Stock Option (right to buy) Ownership: D (Direct) Footnotes: [F12] Options to purchase 1,359 shares vest on each of 6/2/2026 and 6/2/2028; and options to purchase 1,358 shares vest on each of 6/2/2027 and 6/2/2029. [Holding #12] Security: Stock Option (right to buy) Ownership: D (Direct) Footnotes: [F13] Options to purchase 4,788 shares vest on each of 8/15/2026, 8/15/2027 and 8/15/2029; and options to purchase 4,787 shares vest on 8/15/2028. [Holding #13] Security: Performance Restricted Stock Units Ownership: D (Direct) Footnotes: [F1] Each restricted stock unit represents a contingent right to receive one share of Bio-Techne common stock. [F14] Vests in full or in part on 8/15/2028 if certain performance goals are achieved (or such later date as performance is certified by the Administrator). [F14] Vests in full or in part on 8/15/2028 if certain performance goals are achieved (or such later date as performance is certified by the Administrator). [Holding #14] Security: Restricted Stock Units Ownership: D (Direct) Footnotes: [F1] Each restricted stock unit represents a contingent right to receive one share of Bio-Techne common stock. [F15] 245 restricted stock units vest on 3/2/2027, 3/2/2028 and 3/2/2029. [F15] 245 restricted stock units vest on 3/2/2027, 3/2/2028 and 3/2/2029. [Holding #15] Security: Stock Option (right to buy) Ownership: D (Direct) Footnotes: [F16] Options to purchase 478 shares vest on each of 3/2/2027, 3/2/2028 and 3/2/2030; and options to purchase 477 shares vest on 3/2/2029. --- Footnotes (Complete Index) --- F1: Each restricted stock unit represents a contingent right to receive one share of Bio-Techne common stock. F10: Options to purchase 1,832 shares vest on each of 5/1/2025, 5/1/2026 and 5/1/2028; and options to purchase 1,831 shares vest on 5/1/2027. F11: Options to purchase 4,283 shares vest on each of 8/15/2025, 8/15/2027 and 8/15/2028; and options to purchase 4,284 shares vest on 8/15/2026. F12: Options to purchase 1,359 shares vest on each of 6/2/2026 and 6/2/2028; and options to purchase 1,358 shares vest on each of 6/2/2027 and 6/2/2029. F13: Options to purchase 4,788 shares vest on each of 8/15/2026, 8/15/2027 and 8/15/2029; and options to purchase 4,787 shares vest on 8/15/2028. F14: Vests in full or in part on 8/15/2028 if certain performance goals are achieved (or such later date as performance is certified by the Administrator). F15: 245 restricted stock units vest on 3/2/2027, 3/2/2028 and 3/2/2029. F16: Options to purchase 478 shares vest on each of 3/2/2027, 3/2/2028 and 3/2/2030; and options to purchase 477 shares vest on 3/2/2029. F2: 794 restricted stock units vest on 5/1/2026 and 5/1/2027. F3: 600 restricted stock units vest on each of 6/2/2026, 6/2/2027 and 6/2/2028. F4: 1,379 restricted stock units vest on 8/15/2026. F5: 1,868 restricted stock units vest on 8/15/2026 and 1,869 restricted stock units vest on 8/15/2027. F6: 2,176 restricted stock units vest on each of 8/15/2026 and 8/15/2028; and 2,177 restricted stock units vest on 8/15/2027. F7: 100% vested. F8: Options to purchase 6,140 shares vest on each of 8/15/2023, 8/15/2024, 8/15/2025 and 8/15/2026. F9: Options to purchase 3,162 shares vest on each of 8/15/2024, 8/15/2026 and 8/15/2027; and options to purchase 3,163 shares vest on 8/15/2025. --- Signature --- /s/ /s/ Andrew Nick as Attorney-in-Fact for Steven C. Crouse pursuant to Power of Attorney previously filed. (2026-05-05)