Guardant Health (GH) 4: Saia John G. bought 1,020 shares of Common Stock at $N/A on… (Jun 16, 2026)

=== SEC Form 4 — Statement of Changes in Beneficial Ownership === Document Type: 4 Period of Report: 2026-06-15 10b5-1 Pre-arranged Plan: No --- Issuer --- Name: Guardant Health, Inc. (GH) CIK: 0001576280 --- Reporting Owner --- Name: Saia John G. CIK: 0001737840 Role: Officer (Chief Legal Officer) --- Non-Derivative Transactions --- [Transaction #1] Security: Common Stock Date: 2026-06-15 | Code: M (Exercise of derivative) Shares: +1,020 | Price: $0.00 Shares Owned After: 36,970 | Ownership: D (Direct) [Transaction #2] Security: Common Stock Date: 2026-06-15 | Code: F (Payment of exercise/tax) Shares: -535 | Price: $129.82 Total Value: $69,453.70 Shares Owned After: 36,435 | Ownership: D (Direct) Footnotes: [F1] These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability. --- Derivative Transactions --- [Transaction #1] Security: Restricted Stock Units Date: 2026-06-15 | Code: M (Exercise of derivative) Shares: -1,020 | Price: $0.00 Shares Owned After: 0 | Ownership: D (Direct) Footnotes: [F2] This represents a restricted stock unit award granted on June 9, 2023 that vested over a three-year period. 33% of the shares subject to such award vested on June 15, 2024 and the remaining 67% of the shares vested in equal quarterly installments over the remaining two-year period thereafter. [F3] Not applicable for Restricted Stock Units. --- Footnotes (Complete Index) --- F1: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability. F2: This represents a restricted stock unit award granted on June 9, 2023 that vested over a three-year period. 33% of the shares subject to such award vested on June 15, 2024 and the remaining 67% of the shares vested in equal quarterly installments over the remaining two-year period thereafter. F3: Not applicable for Restricted Stock Units. --- Signature --- /s/ /s/ John G. Saia (2026-06-16)